Fluticasone interferes with the activity of which substances in the body?

Fluticasone is a corticosteroid that acts primarily as an anti-inflammatory agent. Its effectiveness comes from its ability to interfere with the activity of multiple inflammatory cytokines, which are signaling molecules that play a crucial role in the inflammatory response. By inhibiting these cytokines, fluticasone helps to reduce inflammation in the airways and other tissues, making it particularly useful in the treatment of conditions such as asthma and allergic rhinitis.

The action of fluticasone on inflammatory cytokines includes reducing the production of inflammatory mediators and suppressing immune responses that lead to inflammation and overactive reactions in the body. Thus, it helps to alleviate symptoms associated with excessive inflammation and contributes to better respiratory function.

Other substances like histamines, prostaglandins, and leukotrienes play different roles in inflammation and allergic responses, but fluticasone's primary effects are most notably linked to a broader range of inflammatory cytokines.