Leukotrienes are released from leukocytes when breathing in what type of substance?

Leukotrienes are inflammatory mediators that play a crucial role in the immune response, particularly in the context of allergic reactions. When allergens, which are typically harmless substances that can trigger an immune response in sensitive individuals, are inhaled, they can stimulate the activation of leukocytes. In response to these allergens, certain leukocytes release leukotrienes, contributing to various symptoms associated with allergic reactions, such as bronchoconstriction and increased mucus production.

This response is key in conditions like asthma and allergic rhinitis, where the immune system overreacts to otherwise innocuous substances. The release of leukotrienes leads to significant physiological effects, making them important targets for therapeutic interventions in allergic conditions. Understanding the role of allergens in triggering leukotriene release helps clarify the mechanisms underlying allergic responses.